Don’t immediately assume that the child your ancestors adopted was not related to them in some way. Depending upon their ages and the ages of their own children, that child could actually be a grandchild. Others may have adopted a niece, nephew or other relative.
Adoptions can impact the DNA matches of any descendant of the child who was adopted. If descendants of the adopted child are DNA matches for some descendants of that child’s adopted siblings, consider the possibility that the adoption was “in the family” in one way or another.
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