Ancestry has released their initial index to the 1950 US Census. It’s not perfect, but for those who have no idea where their person of interest lived, it can be a start.
Make certain to try a variety of searches based on name spellings, residence in 1950, date and place of birth, etc. Remember that information in the enumeration can be incorrect, difficult to read, or transcribed in correctly. Also bear in mind what surname variants will be caught with the various search options. Fortunately a relative of mine whose name was spelled as Niell was easily located.
I’d initially work on the people who are easy to find and go from there. Make certain to review what you think you know about the person in 1950 as well.